Issue 100, 2021
From the journal:

Chemical Communications

A novel near-infrared theranostic probe for accurate cancer chemotherapy in vivo by a dual activation strategy†

Wen-Xin Wang,a   Wen-Li Jiang,a   Guo-Jiang Mao,*b   Zhi-Ke Tan,a   Min Tana  and  Chun-Yan Li ORCID logo *a  

* Corresponding authors

a Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, P. R. China
E-mail: lichunyan79@sina.com

b Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, P. R. China
E-mail: maoguojiang@htu.edu.cn

Abstract

A novel theranostic probe called CX-B-DF is constructed for precise chemotherapy guided by near-infrared (NIR) fluorescence imaging. Moreover, the theranostic probe shows high cytotoxicity to cancer cells under dual activation (H2O2 and TP), which causes the accuracy of drug release to be improved and the toxic side effects to be reduced.

Graphical abstract: A novel near-infrared theranostic probe for accurate cancer chemotherapy in vivo by a dual activation strategy

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Article information

DOI
https://doi.org/10.1039/D1CC05864A
Article type
Communication
Submitted
18 Oct 2021
Accepted
24 Nov 2021
First published
03 Dec 2021

Chem. Commun., 2021,57, 13768-13771

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A novel near-infrared theranostic probe for accurate cancer chemotherapy in vivo by a dual activation strategy

W. Wang, W. Jiang, G. Mao, Z. Tan, M. Tan and C. Li, Chem. Commun., 2021, 57, 13768 DOI: 10.1039/D1CC05864A

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