SCHEDULED MAINTENANCE
The multiple reaction monitoring mode of a triple quadrupole mass spectrometer is used to examine the Buchwald–Hartwig amination reaction at 0.1% catalyst loading in real-time using sequential addition of reagents to probe the individual steps in the cycle. This is a powerful new method for probing reactions under realistic conditions.
G. T. Thomas, E. Janusson, H. S. Zijlstra and J. S. McIndoe, Chem. Commun., 2019, 55, 11727 DOI: 10.1039/C9CC05076K
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