Issue 44, 2016
From the journal:

Chemical Communications

A far-red, photo- and bio-stable fluorescent marker selective to the endoplasmic reticulum and its application to tunicamycin-treated HeLa cells†

Hye-Ri Kim,‡a   Rajesh Kumar,‡b   Woori Kim,a   Jae Hong Lee,a   Myungkoo Suh,a   Amit Sharma,b   Chang Hoe Kim,b   Chulhun Kang*a  and  Jong Seung Kim*b  

* Corresponding authors

a The School of East-West Medical Science, Kyung Hee University, Yongin, Korea
E-mail: kangch@khu.ac.kr

b Department of Chemistry, Korea University, Seoul 136-701, Korea
E-mail: jongskim@korea.ac.kr

Abstract

Herein, we developed an ER selective fluorescent ERp that exhibited a sharp fluorescence emission in the far-red region and high photo- and bio-stability in biological milieu. Its emission is insensitive to pH change and localized in the ER of the cells. Furthermore, it successfully demonstrated that the ER membrane is rapidly reorganized in the perinuclear region by an ER stress inducer, tunicamycin.

Graphical abstract: A far-red, photo- and bio-stable fluorescent marker selective to the endoplasmic reticulum and its application to tunicamycin-treated HeLa cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6CC02330D
Article type
Communication
Submitted
17 Mar 2016
Accepted
03 May 2016
First published
03 May 2016

Chem. Commun., 2016,52, 7134-7137

Permissions

Request permissions

A far-red, photo- and bio-stable fluorescent marker selective to the endoplasmic reticulum and its application to tunicamycin-treated HeLa cells

H. Kim, R. Kumar, W. Kim, J. H. Lee, M. Suh, A. Sharma, C. H. Kim, C. Kang and J. Seung Kim, Chem. Commun., 2016, 52, 7134 DOI: 10.1039/C6CC02330D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements