Issue 1, 2016
From the journal:

RSC Advances

A rhodamine based “turn-on” fluorescent probe for Pb(ii) and live cell imaging†

Omprakash Sunnapu,a   Niranjan G. Kotla,a   Balaji Maddiboyina,c   Subramanian Singaravadivel*b  and  Gandhi Sivaraman*a  

* Corresponding authors

a Institute for Stem Cell Biology and Regenerative Medicine, Bangalore-560065, India
E-mail: raman474@gmail.com, vesp1984@gmail.com

b Department of Chemistry, SSM Institute of Engineering and Technology, Dindigul-624002, India

c Department of Pharmaceutics, Vishwabharathi College of Pharmaceutical Sciences, Guntur, India

Abstract

A novel “turn-on” fluorescent chemosensor RDP-1 based on a rhodamine tri methoxy benzaldehyde conjugate was synthesized, which showed high selectivity and sensitivity towards recognition of Pb2+ in aqueous media over other metal ions and also color changes from colorless to pink, allowing colorimetric detection of Pb2+ by the naked eye. The sensitivity of probe RDP-1 towards Pb2+ was demonstrated in living cells, and can be used for selective imaging of Pb2+ in living cells.

Graphical abstract: A rhodamine based “turn-on” fluorescent probe for Pb(ii) and live cell imaging

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Article information

DOI
https://doi.org/10.1039/C5RA20482H
Article type
Paper
Submitted
03 Oct 2015
Accepted
11 Dec 2015
First published
15 Dec 2015

RSC Adv., 2016,6, 656-660

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A rhodamine based “turn-on” fluorescent probe for Pb(II) and live cell imaging

O. Sunnapu, N. G. Kotla, B. Maddiboyina, S. Singaravadivel and G. Sivaraman, RSC Adv., 2016, 6, 656 DOI: 10.1039/C5RA20482H

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