Issue 1, 2016

A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

Abstract

Palladium catalysed three component cascade process, involving coupling of 2-iodobenzoates, -benzaldehydes, or acetophenones with substituted allenes and ammonium tartrate as an ammonium surrogate, provides a novel and facile route to substituted functionalised isoquinolinones and isoquinolines in good yields.

Graphical abstract: A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

Supplementary files

Article information

Article type
Communication
Submitted
08 Sep 2015
Accepted
21 Oct 2015
First published
21 Oct 2015

Chem. Commun., 2016,52, 164-166

Author version available

A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

R. Grigg, E. E. Elboray, S. Akkarasamiyo, N. Chuanopparat, H. A. Dondas, H. H. Abbas-Temirek, C. W. G. Fishwick, M. F. Aly, B. Kongkathip and N. Kongkathip, Chem. Commun., 2016, 52, 164 DOI: 10.1039/C5CC07526B

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