Issue 34, 2014
From the journal:

RSC Advances

New water soluble Pd-imidate complexes as highly efficient catalysts for the synthesis of C5-arylated pyrimidine nucleosides†

Anant Kapdi,*a   Vijay Gayakhe,a   Yogesh S. Sanghvi,b   Joaquín García,c   Pedro Lozano,d   Ivan da Silva,e   José Pérezf  and  J. Luis Serrano*f  

* Corresponding authors

a Institute of Chemical Technology, Mumbai, Nathalal road, Matunga, Mumbai-400019, India

b Rasayan Inc. 2802, Crystal Ridge Road, Encinitas, California, USA

c Departamento de Químic Inorgánica, Regional Campus of International Excellence “Campus Mare Nostrum” Universidad de Murcia, 30071 Murcia, Spain

d Departamento de Bioquímica y Biología Molecular B eInmunología. Facultad de Química, Regional Campus of International Excellence “Campus Mare Nostrum”, Universidad de Murcia, 30071 Murcia, Spain

e ISIS Facility, Rutherford Appleton Laboratory, Chilton, Oxfordshire, OX11 0QX, UK

f Departamento de Ingeniería Minera, Geológica y Cartográfica. Universidad Politécnica de Cartagena. Área de Química Inorgánica, Regional Campus of International Excellence “Campus Mare Nostrum”, Universidad Politécnica de Cartagena, Cartagena, Spain
E-mail: jose.serrano@upct.es

Abstract

The direct reactions between the precursors trans-[Pd(imidate)2(SMe2)2] and 1,3,5-triaza-7-phosphaadamantane (PTA) yield new water-soluble palladium(II) complexes trans-[Pd(imidate)2(PTA)2](imidate = succinimidate (suc) 1, maleimidate (mal) 2, phthalimidate (phthal) 3 or saccharinate (sacc) 4. The new complexes were revealed as excellent catalysts for environmentally friendly, efficient Suzuki–Miyaura cross-coupling of synthetically challenging substrates like the antiviral nucleoside analogue 5-iodo-2′-deoxyuridine in water as solvent.

Graphical abstract: New water soluble Pd-imidate complexes as highly efficient catalysts for the synthesis of C5-arylated pyrimidine nucleosides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4RA01326C
Article type
Paper
Submitted
14 Feb 2014
Accepted
31 Mar 2014
First published
31 Mar 2014

RSC Adv., 2014,4, 17567-17572

Author version available

Download author version (PDF)

Permissions

Request permissions

New water soluble Pd-imidate complexes as highly efficient catalysts for the synthesis of C5-arylated pyrimidine nucleosides

A. Kapdi, V. Gayakhe, Y. S. Sanghvi, J. García, P. Lozano, I. da Silva, J. Pérez and J. L. Serrano, RSC Adv., 2014, 4, 17567 DOI: 10.1039/C4RA01326C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements