Issue 8, 1994
From the journal:

Journal of the Chemical Society, Chemical Communications

Synthesis of stereospecifically labelled D-prop-2-ynylglycine and investigation of the action of D-amino acid oxidase

Nicola J. Church  and  Douglas W. Young  

Abstract

Stereospecifically deuteriated samples of D-prop-2-ynylglycine 1 are synthesised by reaction of the labelled aziridines 13 with a carbon nucleophile followed by deprotection; incubation of these samples with D-amino acid oxidase indicates that, in formation of the lactone 5, deprotonation at C-3 is non-stereospecific, strongly supporting non-enzymatic deprotonation as a key step in the formation of this compound.

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Article information

DOI
https://doi.org/10.1039/C39940000943
Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 943-944

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Synthesis of stereospecifically labelled D-prop-2-ynylglycine and investigation of the action of D-amino acid oxidase

N. J. Church and D. W. Young, J. Chem. Soc., Chem. Commun., 1994, 943 DOI: 10.1039/C39940000943

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