Issue 5, 2012
From the journal:

Analytical Methods

Multiwalled carbon nanotube paste electrode as an easy, inexpensive and highly selective sensor for voltammetric determination of Risperidone

Abbas Afkhami*a  and  Hamed Ghaedia  

* Corresponding authors

a Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran
E-mail: afkhami@basu.ac.ir
Fax: +98 811 8272404
Tel: +98 811 8272404

Abstract

A carbon paste electrode (CPE) modified with multi-walled carbon nanotube (MWCNT) was proposed for determination of Risperidone (Risp). The method was based on adsorptive accumulation of the Risp on to paste electrode, followed by reduction of the accumulated species by voltammetric scan. The parameters influencing the peak current were optimized. Under the optimum conditions, the electrode established linear response over a wide range of Risp concentrations (0.04 to 10 μmol L−1), the detection limit was 0.012 μmol L−1 (after 150 s accumulation). The method was applied to the determination of Risp in a pharmaceutical preparation and in human serum samples, and satisfactory results were obtained.

Graphical abstract: Multiwalled carbon nanotube paste electrode as an easy, inexpensive and highly selective sensor for voltammetric determination of Risperidone

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Article information

DOI
https://doi.org/10.1039/C2AY05688G
Article type
Paper
Submitted
17 Oct 2011
Accepted
19 Jan 2012
First published
07 Mar 2012

Anal. Methods, 2012,4, 1415-1420

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Multiwalled carbon nanotube paste electrode as an easy, inexpensive and highly selective sensor for voltammetric determination of Risperidone

A. Afkhami and H. Ghaedi, Anal. Methods, 2012, 4, 1415 DOI: 10.1039/C2AY05688G

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