Issue 34, 2011
From the journal:

Journal of Materials Chemistry

Decorating carbon nanotubes with polyethylene glycol-coated magnetic nanoparticles for implementing highly sensitive enzyme biosensors

Reynaldo Villalonga,a   María L. Villalonga,b   Paula Díeza  and  José M. Pingarrón*a  

* Corresponding authors

a Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain
E-mail: pingarro@quim.ucm.es
Fax: +34 913944329
Tel: +34 913944315

b Center for Enzyme Technology, University of Matanzas, Autopista a Varadero km 3 ½, Matanzas, Cuba
E-mail: maria.villalonga@umcc.cu
Fax: +53 45253101
Tel: +53 45261251

Abstract

Superparamagnetic Fe3O4 nanoparticles were coated with (3-aminopropyl)triethoxysilane and further branched with monomethoxypolyethylene glycol chains. These nanoparticles were employed for the non-covalent surface modification of single walled carbon nanotubes, conferring them magnetic properties. This nanomaterial was employed to immobilize the enzyme xanthine oxidase in order to construct magnetically modified disposable gold screen-printed electrodes as bioelectrodes for the determination of xanthine. The electroanalytical properties of the biosensor were modulated by the nanomaterial composition, being optimal at a carbon nanotubes : magnetic nanoparticles ratio of 1 : 27. The resulting biosensor showed a linear dependence on the xanthine concentration in the 0.25–3.5 μM range with a fast amperometric response in 12 s. The biosensor also showed a noticeable high sensitivity of 1.31 A M−1 cm−2 and a very low detection limit of 60 nM, which can be compared advantageously with other biosensor designs for xanthine.

Graphical abstract: Decorating carbon nanotubes with polyethylene glycol-coated magnetic nanoparticles for implementing highly sensitive enzyme biosensors

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Article information

DOI
https://doi.org/10.1039/C1JM11953B
Article type
Paper
Submitted
04 May 2011
Accepted
16 Jun 2011
First published
20 Jul 2011

J. Mater. Chem., 2011,21, 12858-12864

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Decorating carbon nanotubes with polyethylene glycol-coated magnetic nanoparticles for implementing highly sensitive enzyme biosensors

R. Villalonga, M. L. Villalonga, P. Díez and J. M. Pingarrón, J. Mater. Chem., 2011, 21, 12858 DOI: 10.1039/C1JM11953B

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