Issue 39, 2010
From the journal:

Chemical Communications

Real-time monitoring of cell viability by its nanoscale height change with oxygen as endogenous indicator†

Yadong Xue,a   Jianping Lei,a   Xu Xu,a   Lin Ding,a   Chun Zhai,a   Feng Yanb  and  Huangxian Ju*a  

* Corresponding authors

a Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P. R. China
E-mail: hxju@nju.edu.cn
Fax: +86 25 83593593
Tel: +86 25 83593593

b Jiangsu Institute of Cancer Prevention and Cure, Nanjing 210009, P. R. China

Abstract

A method for real-time evaluation of cell viability was developed by using oxygen as an endogenous indicator in scanning electrochemical microscopy to monitor the nanoscale height change of a single cell in a physiological environment with a novel Pt nanodisk electrode and a newly designed step-approaching strategy.

Graphical abstract: Real-time monitoring of cell viability by its nanoscale height change with oxygen as endogenous indicator

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Article information

DOI
https://doi.org/10.1039/C0CC01700K
Article type
Communication
Submitted
02 Jun 2010
Accepted
19 Aug 2010
First published
07 Sep 2010

Chem. Commun., 2010,46, 7388-7390

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Real-time monitoring of cell viability by its nanoscale height change with oxygen as endogenous indicator

Y. Xue, J. Lei, X. Xu, L. Ding, C. Zhai, F. Yan and H. Ju, Chem. Commun., 2010, 46, 7388 DOI: 10.1039/C0CC01700K

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