Issue 6, 2010

Non-α-hydroxylated aldehydes with evolved transketolase enzymes

Abstract

Transketolase mutants previously identified for use with the non-phosphorylated aldehyde propanal have been explored with a series of linear and cyclic aliphatic aldehydes, and excellent stereoselectivities observed.

Graphical abstract: Non-α-hydroxylated aldehydes with evolved transketolase enzymes

Supplementary files

Article information

Article type
Paper
Submitted
18 Nov 2009
Accepted
09 Jan 2010
First published
05 Feb 2010

Org. Biomol. Chem., 2010,8, 1301-1309

Non-α-hydroxylated aldehydes with evolved transketolase enzymes

A. Cázares, J. L. Galman, L. G. Crago, M. E. B. Smith, J. Strafford, L. Ríos-Solís, G. J. Lye, P. A. Dalby and H. C. Hailes, Org. Biomol. Chem., 2010, 8, 1301 DOI: 10.1039/B924144B

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