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Chem. Commun., 2005, 1711 - 1713, DOI: 10.1039/b417727d


Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones

Radovan ebesta, Maria Gabriella Pizzuti, Arnold J. Boersma, Adriaan J. Minnaard and Ben L. Feringa


The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4-piperidones is described.

Graphical abstract image for this article  (ID: b417727d)