Issue 21, 2004

Site-specific oxidative cleavage of DNA by metallosalen–DNA conjugates

Abstract

Ni-salen–DNA conjugates, prepared by template-directed synthesis, targeted oxidative adduct formation and strand scission at deoxyguanosine sites in complementary DNA strands of Watson–Crick duplexes.

Graphical abstract: Site-specific oxidative cleavage of DNA by metallosalen–DNA conjugates

Supplementary files

Article information

Article type
Communication
Submitted
09 Jul 2004
Accepted
05 Aug 2004
First published
24 Sep 2004

Chem. Commun., 2004, 2468-2469

Site-specific oxidative cleavage of DNA by metallosalen–DNA conjugates

J. L. Czlapinski and T. L. Sheppard, Chem. Commun., 2004, 2468 DOI: 10.1039/B410493E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements