Issue 5, 1986

Simultaneous spectrophotometric determination of strychnine and yohimbine in pharmaceutical preparations

Abstract

A spectrophotometric method is proposed for the simultaneous spectrophotometric determination of strychnine.HCl and yohimbine.HCl in pharmaceutical preparations. No preliminary separation step is required. The proposed method involves the use of the modified Vierordt equation. Accurate and reproducible results were obtained. The mean recoveries (six determinations) for strychnine.HCl and yohimbine.HCl were 98.8 ± 0.5% and 100.3 ± 0.8%, respectively. The method was applied to the determination of the two compounds in dosage forms and the results obtained were accurate and precise.

Article information

Article type
Paper

Analyst, 1986,111, 581-583

Simultaneous spectrophotometric determination of strychnine and yohimbine in pharmaceutical preparations

O. Salama and F. Belal, Analyst, 1986, 111, 581 DOI: 10.1039/AN9861100581

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