Issue 0, 1972

4,5-Dihydro-1-benzoxepin-3(2H)-one, N-substituted 2,3-dihydro-1,5-benzoxazepin-4(5H)-ones, and related compounds

Abstract

The preparation of 4,5-dihydro-1-benzoxepin-3(2H)-one and its conversion into 2,3,4,5-tetrahydro-1-benzoxepin-3-amines and related compounds are reported. Ring cleavage of 2,3-dihydro-1,5-benzoxazepin-4(5H)-one to give an acrylamide readily occurs when N-alkylation is attempted. Methods are described for the preparation of some 5-substituted 2,3-dihydro-1,5-benzoxazepin-4(5H)-ones.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1972, 2425-2428

4,5-Dihydro-1-benzoxepin-3(2H)-one, N-substituted 2,3-dihydro-1,5-benzoxazepin-4(5H)-ones, and related compounds

D. Huckle, I. M. Lockhart and M. Wright, J. Chem. Soc., Perkin Trans. 1, 1972, 2425 DOI: 10.1039/P19720002425

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