NH-1,2,3-triazoles as versatile building blocks in denitrogenative transformations
Vladimir
Motornov 
*a
and
Petr
Beier
*a
*a
and
Petr
Beier
*a
Abstract
The utilization of NH-1,2,3-triazoles as easily accessible building blocks in denitrogenative ring cleavage transformations with electrophiles to provide multifunctionalized nitrogen heterocycles and N-alkenyl compounds is reviewed. Leveraging the ready availability of NH-1,2,3-triazoles, these processes provide a convenient route to a range of pharmaceutically relevant heterocyclic cores and N-alkenyl compounds. The synthetic usefulness of in situ acylated NH-1,2,3-triazoles as viable alternatives to widely explored N-sulfonyl-1,2,3-triazoles in ring cleavage processes is highlighted.
- This article is part of the themed collection: 2023 Reviews in RSC Advances
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