Issue 8, 2022
From the journal:

Analyst

Improved discrimination of phenylalanine enantiomers by surface enhanced Raman scattering assay: molecular insight into chiral interaction†

Yanxiu He,‡a   Qinghai Zhou, ORCID logo ‡a   Ning Wang,a   Haifeng Yang ORCID logo *a  and  Xinling Liu ORCID logo *a  

* Corresponding authors

a The Education Ministry Key Lab of Resource Chemistry, College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
E-mail: hfyang@shnu.edu.cn, xlliu@shnu.edu.cn

Abstract

SERS spectroscopy, a nontraditional chiral analysis tool, is used to discriminate between D- and L-phenylalanine (Phe), with the Raman scattering enhancement degree of D-Phe being 50-fold greater than that of L-Phe. Such discrimination is achieved by chiral interactions between Phe and the chiral drug molecule of sertraline on silver coated gold nanorods.

Graphical abstract: Improved discrimination of phenylalanine enantiomers by surface enhanced Raman scattering assay: molecular insight into chiral interaction

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Article information

DOI
https://doi.org/10.1039/D2AN00246A
Article type
Communication
Submitted
10 Feb 2022
Accepted
09 Mar 2022
First published
10 Mar 2022

Analyst, 2022,147, 1540-1543

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Improved discrimination of phenylalanine enantiomers by surface enhanced Raman scattering assay: molecular insight into chiral interaction

Y. He, Q. Zhou, N. Wang, H. Yang and X. Liu, Analyst, 2022, 147, 1540 DOI: 10.1039/D2AN00246A

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