The massive discharge of pollutants including endocrine-disrupting chemicals (EDCs), heavy metals, pharmaceuticals and personal care products (PPCPs) into water bodies is endangering the ecological environment and human health, and needs to be accurately detected. Both electrochemical and photo-electrochemical detection methods have been widely used for the detection of these pollutants, however, which one is better for the detection of different environmental pollutants? In this feature article, different electrochemical and photo-electrochemical detection methods are summarized, including the principles, classification, common catalysts, and applications. By summarizing the advantages and disadvantages of different detection methods, this review provides a guide for other researchers to detect pollutants in water bodies by using electrochemical and photo-electrochemical analysis.