Issue 3, 2019
From the journal:

Natural Product Reports

Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

Alessandro Palmieri ORCID logo a  and  Marino Petrini ORCID logo *a  

* Corresponding authors

a School of Science and Technology, Chemistry Division, University of Camerino, Via S. Agostino, 1 I-62032 Camerino, Italy
E-mail: marino.petrini@unicam.it
Fax: +39 0737 402297
Tel: +39 0737 402253

Abstract

Covering: up to 2018

Tryptophol (indole-3-ethanol) is a metabolite produced by plants, bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and various synthetic approaches to the preparation of tryptophol and its derivatives. Syntheses of various naturally occurring tryptophol derivatives known for their enhanced pharmacological profile are also presented.

Graphical abstract: Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

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Article information

DOI
https://doi.org/10.1039/C8NP00032H
Article type
Review Article
Submitted
05 Apr 2018
First published
19 Sep 2018

Nat. Prod. Rep., 2019,36, 490-530

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Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

A. Palmieri and M. Petrini, Nat. Prod. Rep., 2019, 36, 490 DOI: 10.1039/C8NP00032H

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