Issue 34, 2017
From the journal:

Chemical Communications

Single-molecule imaging of telomerase activity via linear plasmon rulers†

Guang-Sheng Qian,a   Ting-Ting Zhang,a   Wei Zhao,*a   Jing-Juan Xu ORCID logo *a  and  Hong-Yuan Chena  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
E-mail: weizhao@nju.edu.cn, xujj@nju.edu.cn
Fax: +86-25-89687294
Tel: +86-25-89687294

Abstract

Plasmon rulers (PRs) exploit the potential of plasmon coupling between individual pairs of noble metal nanoparticles in biological processes, especially single-molecule detection. Herein, for the first time, we report a strategy based on Ag PRs for in situ monitoring of the extension process of telomerase primer (TSP) activated by a single telomerase.

Graphical abstract: Single-molecule imaging of telomerase activity via linear plasmon rulers

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Article information

DOI
https://doi.org/10.1039/C7CC00626H
Article type
Communication
Submitted
23 Jan 2017
Accepted
28 Mar 2017
First published
31 Mar 2017

Chem. Commun., 2017,53, 4710-4713

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Single-molecule imaging of telomerase activity via linear plasmon rulers

G. Qian, T. Zhang, W. Zhao, J. Xu and H. Chen, Chem. Commun., 2017, 53, 4710 DOI: 10.1039/C7CC00626H

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