Issue 2, 2017

Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(i) trifluoromethanethiolate and selectfluor

Abstract

A straightforward silver-mediated oxidative decarboxylative radical trifluoromethylthiolation reaction of aliphatic carboxylic acid is described. This reaction operates under mild conditions and allows the synthesis of various valuable alkyltrifluoromethylthioethers from abundant alkyl carboxylic acids and convenient nucleophilic AgSCF3 reagent. It provides a practical and efficient approach for the preparation of alkyltrifluoromethylthioethers.

Graphical abstract: Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(i) trifluoromethanethiolate and selectfluor

Supplementary files

Article information

Article type
Paper
Submitted
01 Nov 2016
Accepted
16 Nov 2016
First published
03 Jan 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 880-883

Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(I) trifluoromethanethiolate and selectfluor

B. He, Z. Xiao, H. Wu, Y. Guo, Q. Chen and C. Liu, RSC Adv., 2017, 7, 880 DOI: 10.1039/C6RA26133G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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