* Corresponding authors

^a School of Pharmacy, China Medical University, Taichung 404, Taiwan

^b Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan

^c Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
E-mail: sheu@mail.nsysu.edu.tw
Fax: +886-7-5255020
Tel: +886-7-5252000 ext. 5030

^d Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan

^e Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan

^f Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan

^g Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan