Issue 60, 2014
From the journal:

RSC Advances

Growth kinetics of gold nanoparticles on silica/graphene surfaces for multiplex biological immunoassays†

Rouslan V. Olkhova  and  Andrew M. Shaw*a  

* Corresponding authors

a College of Life and Environmental Sciences, University of Exeter, Stocker Road, Exeter, UK
E-mail: andrew.m.shaw@exeter.ac.uk

Abstract

Kinetics of seed-mediated chemical growth of gold nanoparticles on silica substrates coated with a thin layer of graphene-derivative materials were studied with the ultimate goal of employing the developed graphene–nanoparticle composites in light-scattering imaging biosensor applications. The type of the surface coating and chemical conditions influence the surface number density and size of the grown nanoparticles. Importantly, when used as biosensor bases, the substrates coated with protein reduced graphene oxide have shown beneficial biological compatibility towards immobilized antibodies resulting in about 20-fold improvement in antigen capture by the antibodies tethered to the sensor surface in immunoassay performed on the multiplex photonic biosensor platform.

Graphical abstract: Growth kinetics of gold nanoparticles on silica/graphene surfaces for multiplex biological immunoassays

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4RA02326A
Article type
Paper
Submitted
17 Mar 2014
Accepted
11 Jul 2014
First published
14 Jul 2014

RSC Adv., 2014,4, 31678-31684

Author version available

Download author version (PDF)

Permissions

Request permissions

Growth kinetics of gold nanoparticles on silica/graphene surfaces for multiplex biological immunoassays

R. V. Olkhov and A. M. Shaw, RSC Adv., 2014, 4, 31678 DOI: 10.1039/C4RA02326A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements