Issue 19, 1985

Total synthesis of optically active 17β-t-butoxy-3-methoxy-7α- or -7β-18-dimethyl-1,3,5(10)-estratriene

Abstract

In the preparation of 7-methyl-19-nor-steroids, a new method for the synthesis of key intermediates (10), which involves alkylation of the CD ring fragment (4) and subsequent hydrogenation, cyclization, and hydrogenation is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1985, 1277-1278

Total synthesis of optically active 17β-t-butoxy-3-methoxy-7α- or -7β-18-dimethyl-1,3,5(10)-estratriene

Z. Cai, Y. Ni, J. Sun, X. Yu and Y. Wang, J. Chem. Soc., Chem. Commun., 1985, 1277 DOI: 10.1039/C39850001277

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