Issue 6, 2011
From the journal:

Nanoscale

Reactions inside nanoscale protein cages

Saskia A. Bode,a   Inge J. Minten,a   Roeland J. M. Noltea  and  Jeroen J. L. M. Cornelissen*ab  

* Corresponding authors

a Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, Nijmegen, The Netherlands
E-mail: j.j.l.m.cornelissen@utwente.nl
Fax: +31 53 4894645
Tel: +31 53 4894380

b Laboratory for Biomolecular Nanotechnology, MESA+ Institute for Nanotechnology, University of Twente, PO Box 217, Enschede, The Netherlands

Abstract

Chemical reactions are traditionally carried out in bulk solution, but in nature confined spaces, like cell organelles, are used to obtain control in time and space of conversion. One way of studying these reactions in confinement is the development and use of small reaction vessels dispersed in solution, such as vesicles and micelles. The utilization of protein cages as reaction vessels is a relatively new field and very promising as these capsules are inherently monodisperse, in that way providing uniform reaction conditions, and are readily accessible to both chemical and genetic modifications. In this review, we aim to give an overview of the different kinds of nanoscale protein cages that have been employed as confined reaction spaces.

Graphical abstract: Reactions inside nanoscale protein cages

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Article information

DOI
https://doi.org/10.1039/C0NR01013H
Article type
Review Article
Submitted
21 Dec 2010
Accepted
07 Feb 2011
First published
04 Apr 2011

Nanoscale, 2011,3, 2376-2389

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Reactions inside nanoscale protein cages

S. A. Bode, I. J. Minten, R. J. M. Nolte and J. J. L. M. Cornelissen, Nanoscale, 2011, 3, 2376 DOI: 10.1039/C0NR01013H

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