Issue 7, 2010
From the journal:

Dalton Transactions

Areneruthenium complexes as anticancer agents†

Georg Süss-Fink*a  

* Corresponding authors

a Institut de Chimie, Université de Neuchâtel, Case postale 158, CH-2009 Neuchâtel, Switzerland
E-mail: georg.suess-fink@unine.ch
Fax: +41 32 718 2511
Tel: +41 32 718 2405

Abstract

Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high potential for the development of metal-based anticancer drugs. Mononuclear arene ruthenium complexes containing P- or N-donor ligands or N,N-, N,O- or O,O-chelating ligands, dinuclear arene ruthenium systems with adjustable organic linkers, trinuclear arene ruthenium clusters containing an oxo cap, tetranuclear arene ruthenium porphyrin derivatives that are photoactive, as well as hexanuclear ruthenium cages that are either empty or filled with other molecules have been shown to be active against a variety of cancer cells.

Graphical abstract: Arene ruthenium complexes as anticancer agents

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Article information

DOI
https://doi.org/10.1039/B916860P
Article type
Perspective
Submitted
14 Aug 2009
Accepted
23 Sep 2009
First published
23 Oct 2009

Dalton Trans., 2010,39, 1673-1688

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Arene ruthenium complexes as anticancer agents

G. Süss-Fink, Dalton Trans., 2010, 39, 1673 DOI: 10.1039/B916860P

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