Issue 0, 1985
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Chiral α-sulphinyl hydrazones as effective reagents for stereoselective aldol-type condensation

Rita Annunziata,   Franco Cozzi,   Mauro Cinquini,   Lino Colombo,   Cesare Gennari,   Giovanni Poli  and  Carlo Scolastico  

Abstract

The stereoselective aldol-type synthesis of optically active β-hydroxy hydrazones and β-hydroxy ketones mediated by chiral α-sulphinyl hydrazones is described. In some cases a good degree of enantioselectivity (up to 88%) is achieved. The factors affecting the stereochemical outcome of the process, i.e. the nature and stoicheiometry of the base and the structures and steric requirements of the α-sulphinyl hydrazones are discussed.

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Article information

DOI
https://doi.org/10.1039/P19850000251
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1985, 251-254

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Chiral α-sulphinyl hydrazones as effective reagents for stereoselective aldol-type condensation

R. Annunziata, F. Cozzi, M. Cinquini, L. Colombo, C. Gennari, G. Poli and C. Scolastico, J. Chem. Soc., Perkin Trans. 1, 1985, 251 DOI: 10.1039/P19850000251

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