Issue 15, 2011
From the journal:

Soft Matter

Lysozyme fibrillation induced by convective flow under quasi contact-free conditions†

Angelo Accardo,abc   Manfred Burghammer,b   Emanuela Di Cola,b   Michael Reynolds,b   Enzo Di Fabrizioac  and  Christian Riekel*b  

* Corresponding authors

a Center of Bio-Nanotechnology and Engineering for Medicine, University Magna Græcia, Viale Europa, Catanzaro, Italy

b European Synchrotron Radiation Facility, B.P. 220, Grenoble Cedex, France
E-mail: angelo.accardo@esrf.fr, burghammer@esrf.fr, dicola@esrf.fr, michael.reynolds@esrf.fr, riekel@esrf.fr

c Italian Institute of Technology, Via Morego, Genova, Italy
E-mail: enzo.difabrizio@iit.it

Abstract

The evaporation of a lysozyme solution drop containing Ca2+ ions on a superhydrophobic poly(methyl methacrylate) surface was probed by X-ray microbeam raster-diffraction. We observe the rapid deposition of fibrillar lysozyme with amyloidic cross-β structure at the interface of the drop with the substrate under conditions of weak acidity, close to physiological.

Graphical abstract: Lysozyme fibrillation induced by convective flow under quasi contact-free conditions

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Article information

DOI
https://doi.org/10.1039/C1SM05783A
Article type
Communication
Submitted
29 Apr 2011
Accepted
27 May 2011
First published
13 Jun 2011

Soft Matter, 2011,7, 6792-6796

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Lysozyme fibrillation induced by convective flow under quasi contact-free conditions

A. Accardo, M. Burghammer, E. Di Cola, M. Reynolds, E. Di Fabrizio and C. Riekel, Soft Matter, 2011, 7, 6792 DOI: 10.1039/C1SM05783A

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