Issue 10, 2009
From the journal:

Molecular BioSystems

Mitochondrial proteomics and its application in biomedical research

Cristina Ruiz-Romeroa  and  Francisco J. Blanco*a  

* Corresponding authors

a Laboratorio de Investigación Osteoarticular y del Envejecimiento, Unidad de Proteómica – Nodo Asociado a ProteoRed, INIBIC-Complejo Hospitalario Universitario A Coruña, 15006-A Coruña
E-mail: Francisco.Blanco.García@sergas.es
Fax: +34 981-178273
Tel: +34 981-178272

Abstract

Mitochondria are essential organelles that play key roles in a number of cellular processes. Therefore, it is not surprising that DNA mutations and mitochondrial protein dysfunctions have been associated with several diseases, aging and tumorigenic processes. To date, proteomic strategies have increased our knowledge about the functions of mitochondrial proteins. The use of proteomics technology will be essential to expand the analysis of mitochondrial protein dysfunctions and their pathogenic features. This review will focus on the state-of-art proteomic strategies in mitochondrial research, and their application to biomedicine.

Graphical abstract: Mitochondrial proteomics and its application in biomedical research

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B906296N
Article type
Review Article
Submitted
30 Mar 2009
Accepted
16 Jul 2009
First published
03 Aug 2009

Mol. BioSyst., 2009,5, 1130-1142

Permissions

Request permissions

Mitochondrial proteomics and its application in biomedical research

C. Ruiz-Romero and F. J. Blanco, Mol. BioSyst., 2009, 5, 1130 DOI: 10.1039/B906296N

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements