Issue 7, 2012
From the journal:

Chemical Society Reviews

Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents†

Nohyun Leea  and  Taeghwan Hyeon*a  

* Corresponding authors

a World Class University Program of Chemical Convergence for Energy & Environment, and School of Chemical and Biological Engineering, Seoul National University, Seoul, Korea
E-mail: thyeon@snu.ac.kr

Abstract

Various magnetic nanoparticles have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents owing to their unique characteristics, including efficient contrast effects, biocompatibility, and versatile surface functionalization capability. Nanoparticles with high relaxivity are very desirable because they would increase the accuracy of MRI. Recent progress in nanotechnology enables fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. In this tutorial review, we discuss how MRI contrast effects can be improved by controlling the size, composition, doping, assembly, and surface properties of iron-oxide-based nanoparticles.

Graphical abstract: Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents

  • This article is part of the themed collection: Nanomedicine
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Article information

DOI
https://doi.org/10.1039/C1CS15248C
Article type
Tutorial Review
Submitted
11 Sep 2011
First published
02 Dec 2011

Chem. Soc. Rev., 2012,41, 2575-2589

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Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents

N. Lee and T. Hyeon, Chem. Soc. Rev., 2012, 41, 2575 DOI: 10.1039/C1CS15248C

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