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Cell fate determination from stem cells

Gene Therapy volume 9, pages 606–612 (2002)Cite this article

Abstract

In the adult, tissue-specific stem cells are thought to be responsible for the replacement of differentiated cells within continuously regenerating tissues, such as the liver, skin, and blood system. In this review, we will consider the factors that influence stem cell fate, taking as a primary example the cell fate determination of hematopoietic stem cells.

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  1. A J Wagers and J L Christensen: The first two authors contributed equally to this work

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  1. Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA

    A J Wagers, J L Christensen & I L Weissman

  2. Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA

    I L Weissman

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  2. J L Christensen
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Wagers, A., Christensen, J. & Weissman, I. Cell fate determination from stem cells. Gene Ther 9, 606–612 (2002). https://doi.org/10.1038/sj.gt.3301717

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