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Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe

Bone Marrow Transplantation volume 29, pages 639–646 (2002)Cite this article

Abstract

The Accreditation Sub-Committee of the EBMT regularly publishes special reports on current practice of haemopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders. Major changes have occurred since the last report in 1998. Haemopoietic stem cell transplantation today includes allogeneic and autologous stem cells derived from bone marrow, peripheral blood and cord blood. With reduced intensity conditioning regimens in allogeneic transplantation, the age limit has increased, permitting the inclusion of older patients. New indications have emerged, such as autoimmune disorders and AL amyloidosis for autologous, and solid tumours for allogeneic transplants. Other indications, such as autologous transplantation for breast cancer have been challenged. An updated report with revised tables and operating definitions is presented here.

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References

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Acknowledgements

The authors are grateful for the advice and helpful comments received from a number of individuals across Europe specialising in the use of haemopoietic stem cell transplantation to treat patients with haematological disorders. Special thanks to T Ruutu, JJ Ortega, G Sanz, F Prosper, E Montserrat, P Corradini and P Dreger.

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Authors and Affiliations

  1. Dept of Hematology, Hospital Clinic, Barcelona, Spain

    A Urbano-Ispizua

  2. Dept of Hematology, AK St Georg, Hamburg, Germany

    N Schmitz

  3. Dept of Hematology, University Medical Center St. Radboud, Nijmegen, The Netherlands

    T de Witte

  4. Dept of Hematology, Ospedale, San Martino, Genova, Italy

    F Frassoni

  5. Dept of Onco-Hematology, Ospedale Civile, Ravenna, Italy

    G Rosti

  6. Dept of Hematology, Oncology, Transfusion Med, University Hospital Benjamin Franklin, Berlin, Germany

    H Schrezenmeier

  7. Dept of Hematology, BMT Unit, Hôpital St. Louis, Paris, France

    E Gluckman & G Socie

  8. Abt Pädiatrie II, University of Ulm, Ulm, Germany

    W Friedrich

  9. Dept of Hematology, Hôpital Henri Mondor, Créteil, France

    C Cordonnier

  10. Reumatologische Universitätsklinik, Felix Platter Spital, Basel, Switzerland

    A Tyndall

  11. Dept of Pediatrics, University Hospital, Tübingen, Germany

    D Niethammer

  12. Dept of Hematology, Huddinge University Hospital, Huddinge, Sweden

    P Ljungman

  13. Dept of Hematology, Kantonsspital, Basel, Switzerland

    A Gratwohl

  14. Dept of Haematology, Imperial College School of Medicine, Hammersmith Hospital, London, UK

    J Apperley & A Bacigalupo

  15. Div Internal Med II, University of Leipzig, Germany

    D Niederwieser

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  1. A Urbano-Ispizua
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  2. N Schmitz
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  3. T de Witte
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  4. F Frassoni
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  5. G Rosti
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  6. H Schrezenmeier
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  7. E Gluckman
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  8. W Friedrich
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  9. C Cordonnier
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  10. G Socie
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  11. A Tyndall
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  12. D Niethammer
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  13. P Ljungman
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  14. A Gratwohl
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  15. J Apperley
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  16. D Niederwieser
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  17. A Bacigalupo
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Urbano-Ispizua, A., Schmitz, N., de Witte, T. et al. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe. Bone Marrow Transplant 29, 639–646 (2002). https://doi.org/10.1038/sj.bmt.1703535

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  • DOI: https://doi.org/10.1038/sj.bmt.1703535

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