Mouse embryonic organoids that model cardiac development ex vivo could be used as a high-throughput, experimentally tractable system to evaluate crucial cell populations and environmental factors that contribute to normal and abnormal cardiogenesis.
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Acknowledgements
The authors thank K. Claiborn (Gladstone Institutes, San Francisco, CA, USA) for editorial assistance and A. Silva (Gladstone Institutes, San Francisco, CA, USA) for assistance with preparing the figure before submission.
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Srivastava, D., McDevitt, T.C. Mouse gastruloids take heart. Nat Rev Cardiol 18, 233–234 (2021). https://doi.org/10.1038/s41569-020-00501-4
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DOI: https://doi.org/10.1038/s41569-020-00501-4
