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STEM CELLS

The reprogramming method matters

A Publisher Correction to this article was published on 02 January 2018

This article has been updated

The genetic, epigenetic and transcriptomic profiles of human induced pluripotent stem cells are shaped by the reprogramming route.

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Fig. 1: hiPSCs generated by different reprogramming methods have distinct genetic, epigenetic and transcriptomic patterns from one another and from hESCs.

Change history

  • 02 January 2018

    In the version of this News and Views article originally published, an erroneous hyphen was included in the term ‘human-induced pluripotent stem cells’; it should have read ‘human induced pluripotent stem cells’. This error has now been corrected in all versions of the News and Views article.

References

  1. Takahashi, K. et al. Cell 131, 861–872 (2007).

    Article  CAS  PubMed  Google Scholar 

  2. Bock, C. et al. Cell 144, 439–452 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Chin, M., Mason, M., Xie, W., Volinia, S. & Singer, M. Cell Stem Cell 5, 111–123 (2009).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Ruiz, S. et al. Proc. Natl Acad. Sci. USA 109, 16196–16201 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Churko, J. M. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-017-0141-6 (2017).

    Article  Google Scholar 

  6. Amps, K. et al. Nat. Biotech 29, 1132–1144 (2011).

    Article  CAS  Google Scholar 

  7. Baker, D. et al. Stem Cell Rep 7, 998–1012 (2016).

    Article  CAS  Google Scholar 

  8. Huangfu, D. et al. Nat. Biotechnol. 26, 795–797 (2008).

    Article  CAS  PubMed  Google Scholar 

Download references

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Correspondence to William E. Lowry.

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A correction to this article is available online at https://doi.org/10.1038/s41551-017-0170-1.

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Allison, T.F., Lowry, W.E. The reprogramming method matters. Nat Biomed Eng 1, 779–781 (2017). https://doi.org/10.1038/s41551-017-0148-z

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