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Li-Eswt improves hemodynamic parameters thus suggesting neoangiogenesis in patients with vascular erectile dysfunction

International Journal of Impotence Research volume 34, pages 237–242 (2022)Cite this article

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Abstract

Extracorporeal treatment with low intensity shock-wave therapy (LI-ESWT) is a recently introduced non-invasive method which purposes the restoration of the pathophysiological alterations at the base of vasculogenic ED in male patients. The evidence in favour of the neoangiogenic potential of this treatment derived from in vitro studies and on animal models. The purpose of this study, in which the Power Doppler method was applied, is to demonstrate ‘objectively’ the real efficacy of LI-ESWT at the level of the microcirculation of the corpora cavernosa (neoangiogenesis) in patients affected by vasculogenic ED. Data from this study show, for the first time, that LI-ESWT treatment promotes neovascularisation of the functional arteries in patients affected by vasculogenic ED.

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Fig. 1: Sphygmomanometer.
Fig. 2: Penile power doppler.
Fig. 3: Statistical analysis.

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Authors and Affiliations

  1. Department of Urology and Andrology, Ospedale di Circolo and Macchi Foundation, Varese, Italy

    Fabrizio I. Scroppo, Matteo Malfatto, Paolo Capogrosso & Federico Dehò

  2. Centro Medico Unisalus, Milano, Italy

    Fabio Pezzoni

  3. Surgery Department, Urology and Andrology Unit; Military Hospital of Milan, Milano, Italy

    Francesco Gaeta

  4. “La Sapienza” University of Rome; Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies; Urology Univ, Latina, Italy

    Luigi A. Pastore

  5. University of Insubria, Varese, Italy

    Matteo Malfatto & Federico Dehò

  6. Department of Urology, Santa Chiara Regional Hospital, Trento, Italy

    Tommaso Cai

  7. Department of Translationals Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

    Alessandro Zucchi

Authors
  1. Fabrizio I. Scroppo
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  2. Fabio Pezzoni
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  3. Francesco Gaeta
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  4. Luigi A. Pastore
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  6. Tommaso Cai
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  8. Federico Dehò
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  9. Alessandro Zucchi
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Correspondence to Alessandro Zucchi.

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Scroppo, F.I., Pezzoni, F., Gaeta, F. et al. Li-Eswt improves hemodynamic parameters thus suggesting neoangiogenesis in patients with vascular erectile dysfunction. Int J Impot Res 34, 237–242 (2022). https://doi.org/10.1038/s41443-021-00411-0

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  • DOI: https://doi.org/10.1038/s41443-021-00411-0

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