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Controversies and challenges in HLA-haplotype-matched transplants for leukaemia

Abstract

Many typescripts in this issue describe increasing use of HLA-haplotype-matched transplants in persons with leukaemia and report outcomes. Consequently, my goal is not to repeat these data but to focus on controversies and challenges relevant to this topic including: (1) what is the best technique for performing these transplants; (2) who is the best donor; (3) who should receive this type of transplant; (4) how do results compare with transplants from other donors; and (5) how can results be improved.

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Funding

Publication of this supplement was sponsored by Gilead Sciences Europe Ltd, Cell Source, Inc., The Chorafas Institute for Scientific Exchange of the Weizmann Institute of Science, Kiadis Pharma, Miltenyi Biotec, Celgene, Centro Servizi Congressuali, Almog Diagnostic.

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Correspondence to Robert Peter Gale.

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Gale, R.P. Controversies and challenges in HLA-haplotype-matched transplants for leukaemia. Bone Marrow Transplant 54 (Suppl 2), 719–720 (2019). https://doi.org/10.1038/s41409-019-0611-4

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  • DOI: https://doi.org/10.1038/s41409-019-0611-4

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