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ACEing GPI release

A recent study shows that the testicular angiotensin converting enzyme (ACE) has a new unexpected activity: it is responsible for cleaving GPI off from proteins anchored on the sperm cell membrane.

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Figure 1: Release of GPI-anchored proteins during sperm cell capacitation.

K. Ris

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Mayor, S. ACEing GPI release. Nat Struct Mol Biol 12, 107–108 (2005). https://doi.org/10.1038/nsmb0205-107

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