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Defective protein folding as a cause of disease

A defined, spontaneous protein folding defect can act as a common link between lung and liver diseases associated with the Z type of plasma α1-antitrypsin deficiency.

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Sifers, R. Defective protein folding as a cause of disease. Nat Struct Mol Biol 2, 355–357 (1995). https://doi.org/10.1038/nsb0595-355

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