Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Iron acquisition: straight up and on the rocks?

New structural analysis finds a metal-oxo clusters bound to the iron trafficking protein Fbp. Does this point to a possible strategy for bacterial iron acquisition?

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Stylized view of iron acquisition pathways by Gram-negative bacteria.

Figure courtesy of Peter Allen.

References

  1. Alexeev, D. et al. Nat. Struct. Biol. 10, 297–302 (2003).

    Article  CAS  Google Scholar 

  2. Lankford, C.E. CRC Crit. Rev. Microbiol. 2, 273–331 (1973).

    Article  CAS  Google Scholar 

  3. Ferreiros, C., Criado, M.T., & Gomez, J.A. Comp. Biochem. Physiol. B, 123, 1–7 (1999).

    Article  CAS  Google Scholar 

  4. Aisen, P. in Metal Ions in Biological Systems Vol. 35 (eds. Sigel, A. and Sigel, H.) 585–631 (Marcel Dekker, New York; 1998).

    Google Scholar 

  5. Taboy, C.H., Vaughan, K.G., Mietzner, T.A., Aisen, P. & Crumblis, A.L. J. Biol. Chem. 176, 2719–2714 (2001).

    Article  Google Scholar 

  6. Ledyard, K.M. & Butler, A. J. Biol. Inorg. Chem., 2, 93–97 (1997).

    Article  CAS  Google Scholar 

  7. Heidelberg, J.F. et al. Nat. Biotechnol. 20, 1118–1123 (2002).

    Article  CAS  Google Scholar 

  8. Lower, S.K., Hochella, M.F. Jr. & Beveridge, T.J. Science 292, 1360–1363 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Butler, A. Iron acquisition: straight up and on the rocks?. Nat Struct Mol Biol 10, 240–241 (2003). https://doi.org/10.1038/nsb0403-240

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsb0403-240

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing