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Prostate cancer

Microbiome — the 'unforeseen organ'

The advent of molecular methods for the identification and characterization of the microbiome has led researchers to understand the role of the microbiota in various clinical conditions. Research by Cavarretta and colleagues has revealed the presence of microbial dysbiosis and its potential relationship with pathophysiology in the prostate tumour microenvironment. This finding could potentially enable future investigations that clarify the role of the microbiota in the development of prostate cancer and its future management, from a different perspective.

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References

  1. Whiteside, S. A. et al. The microbiome of the urinary tract — a role beyond infection. Nat. Rev. Urol. 12, 81–90 (2015).

    Article  Google Scholar 

  2. Siegel, R. L. et al. Cancer statistics 2017. CA Cancer J. Clin. 67, 7–30 (2017).

    Article  Google Scholar 

  3. National Cancer Institute. Surveillance, Epidemiology and End Results Program. Cancer stat facts: prostate cancer. NIH http://www.seer.cancer.gov/statfacts/html/prost.html (2014).

  4. Wolk, A. Diet, lifestyle and risk of prostate cancer. Acta Oncol. 44, 277–281 (2005).

    Article  Google Scholar 

  5. Amirian, E. S. et al. Potential role of gastrointestinal microbiota composition in prostate cancer risk. Infect. Agent Cancer 8, 42 (2013).

    Article  Google Scholar 

  6. Cavarretta, I. et al. The microbiome of the prostate tumor microenvironment. Eur. Urol. http://dx.doi.org/10.1016/j.eururo.2017.03.029 (2017).

  7. Schwabe, R. F. et al. The microbiome and cancer. Nat. Rev. Cancer 13, 800–812 (2013).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Muhammed A.P. Manzoor.

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Manzoor, M., Rekha, P. Microbiome — the 'unforeseen organ'. Nat Rev Urol 14, 521–522 (2017). https://doi.org/10.1038/nrurol.2017.97

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