Abstract

It has been almost 25 years since Doll and Peto performed their landmark analysis of epidemiological data to identify the causes of cancers and possible modes of cancer prevention. Since then, there have been many additional studies of cancer incidence using various epidemiological techniques. These studies revealed expanded opportunities for cancer prevention through approaches that include vaccination, increased physical activity, weight control and avoidance of post-menopausal hormone therapy.

Author affiliations

1. Graham A. Colditz is at the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
2. Thomas A. Sellers is at the H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA.
3. Edward Trapido is at the Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, EPN 5112, 6130 Executive Boulevard, Bethesda, Maryland 20852, USA.

Correspondence to: Graham A. Colditz¹ Email: Graham.Colditz@channing.harvard.edu

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