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The tail does not always wag the dog

Nature Genetics volume 32, pages 221–222 (2002)Cite this article

There is a growing awareness of the importance of chromatin modifications in regulating everything from gene expression to DNA replication. A new study extends our knowledge of how certain regions of the yeast genome are silenced into transcriptionally inactive domains, and offers strong evidence for new structural principles that may govern this process. These findings require us to revise our histone tail–centric view of chromatin silencing and other processes that affect chromatin structure.

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  1. Department of Biochemistry & Molecular Biology, Colorado State University, Fort Collins, 80523, Colorado, USA

    Karolin Luger

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  1. Karolin Luger
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Luger, K. The tail does not always wag the dog. Nat Genet 32, 221–222 (2002). https://doi.org/10.1038/ng1000

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