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Chromosome instability leaves its mark

Genomic instability is a common feature of human cancer. A new study identifies a putative gene expression signature of chromosome instability in solid tumors, with implications for both understanding the underlying mechanisms and improving prediction of clinical outcomes.

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Figure 1

Image courtesy of Charles Lee

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Pollack, J. Chromosome instability leaves its mark. Nat Genet 38, 973–974 (2006). https://doi.org/10.1038/ng0906-973

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