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Mitotic Inhibition and Nucleic Acid Synthesis in Amoeba Nuclei

Abstract

SEVERAL strains of large mononucleate amoebae contain specific proteins which inhibit mitosis and eventually kill amoebae of strains other than their own1,2. We now describe experiments to show that this lethal antimitotic factor (AF) inhibits RNA synthesis when injected into susceptible cells.

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JEON, K., LORCH, I. Mitotic Inhibition and Nucleic Acid Synthesis in Amoeba Nuclei. Nature New Biology 231, 91–93 (1971). https://doi.org/10.1038/newbio231091a0

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