Research Highlights

Nature Clinical Practice Nephrology (2008) 4, 242
doi:10.1038/ncpneph0791  

UNOS criteria identify candidates for organ donation after cardiac death

This article has no abstract so we have provided the first paragraph of the full text.

Organs from patients who died more than 60 min after the withdrawal of life-sustaining treatment (LST) are generally considered unsuitable for transplantation because warm ischemia impairs organ function. Donation after cardiac death is uncommon in the US, partly as a result of the difficulty of prospectively identifying patients who are likely to die within the 60 min window. To facilitate the identification of such individuals, the United Network for Organ Sharing (UNOS) developed a set of criteria in 2002. These criteria have now been validated for the first time, in a prospective study of 505 adults who underwent elective withdrawal of LST at five US hospitals.

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