Abstract
Background A 19-year-old white woman presented with a 6-month history of progressively worsening dysphagia.
Investigations Esophagogastroduodenoscopy, esophageal biopsies followed by histological evaluation of biopsy samples including immunohistochemical staining for herpes simplex virus.
Diagnosis Herpes esophagitis with concurrent eosinophilic esophagitis.
Management Valaciclovir and fluconazole.
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References
Attwood SE et al. (1993) Esophageal eosinophilia with dysphagia. A distinct clinicopathologic syndrome. Dig Dis Sci 38: 109–116
Blanchard C and Rothenberg ME (2008) Basic pathogenesis of eosinophilic esophagitis. Gastrointest Endosc Clin N Am 18: 133–143
Gonsalves N (2008) Eosinophilic esophagitis: history, nomenclature, and diagnostic guidelines. Gastrointest Endosc Clin N Am 18: 1–9
Chehade M and Sampson HA (2008) Epidemiology and etiology of eosinophilic esopohagitis. Gastointest Endosc Clin N Am 18: 33–44
Furata GT et al. (2007) Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology 133: 1342–1363
Fox VL (2008) Eosinophilic esophagitis: endoscopic findings. Gastointest Endosc Clin N Am 18: 45–57
Rodrigo S et al. (2008) High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults. Am J Gastroenterol 103: 435–442
Ngo P et al. (2006) Eosinophils in the esophagus—peptic or allergic eosinophilic esophagitis? Case series of three patients with esophageal eosinophlia. Am J Gastroenterol 101: 1666–1670
Ramanathan J et al. (2000) Herpes simplex virus esophagitis in the immunocompetent host. Am J Gastroenterol 95: 2171–2176
Aceves SS et al. (2008) Integrated approach to treatment of children and adults with eosinophilic esophagits. Gastrointest Endosc Clin N Am 18: 195–217
Noel RJ et al. (2004) Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. Clin Gastroenterol Hepatol 2: 568–575
Remedios MR et al. (2006) Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate. Gastrointest Endosc 63: 3–12
Konikoff MR et al. (2006) A randomized, double-blind, placebo-controlled trial of fluticasone proprionate for pediatric eosinophilic esophagitis. Gastroenterology 131: 1381–1391
Aceves SS et al. (2007) Oral viscous budesonide: a potential new therapy for eosinophilic esophagitis. Am J Gastroenterol 102: 2271–2279
Straumann A (2008) The natural history and complications of eosinophilic esophagitis. Gastointest Endosc Clin N Am 18: 99–118
Acknowledgements
The authors would like to thank Kevin Struckhoff for his assistance.
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Guy Lindberg and Mohammad H Saboorian are stock-holders/directors of Caris Diagnostics. Richard Van Eldik declared no competing interests.
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Lindberg, G., Van Eldik, R. & Saboorian, M. A case of herpes esophagitis after fluticasone propionate for eosinophilic esophagitis. Nat Rev Gastroenterol Hepatol 5, 527–530 (2008). https://doi.org/10.1038/ncpgasthep1225
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DOI: https://doi.org/10.1038/ncpgasthep1225