A potent and selective inhibitor for the protein lysine methyltransferases G9a and GLP has been discovered. This small molecule serves as a useful probe to decipher the specific role of these enzymes in the development of various diseases.
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Hauser, AT., Jung, M. Sharpen your epigenetic tools. Nat Chem Biol 7, 499–500 (2011). https://doi.org/10.1038/nchembio.615
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DOI: https://doi.org/10.1038/nchembio.615
