A process in which peptide nucleic acids may be used for in vitro evolution has been developed. This method can offer enormous opportunities to evolve stable, non-natural molecules for therapeutic applications.
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Appella, D. Overcoming biology's limitations. Nat Chem Biol 6, 87–88 (2010). https://doi.org/10.1038/nchembio.300
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DOI: https://doi.org/10.1038/nchembio.300