News and Views
Nature Cell Biology 9, 249 - 251 (2007)
doi:10.1038/ncb0307-249
Mural cells paint a new picture of muscle stem cells
Jennifer Morgan1 & Francesco Muntoni1
- Jennifer Morgan and Francesco Muntoni are in the Dubowitz Neuromuscular Unit, Department of Paediatrics, Division of Medicine, Imperial College, Du Cane Road, London W12 0NN, UK. e-mail: jennifer.morgan@imperial.ac.uk; e-mail: f.muntoni@imperial.ac.uk
Abstract
Despite being largely a post-mitotic tissue, adult skeletal muscle exhibits a remarkable capacity for regeneration. A new study has shown that cells derived from mural cells (pericytes) from blood vessels in postnatal human skeletal muscle contribute to robust skeletal muscle regeneration after intra-arterial delivery into a dystrophic mouse model.
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