1. Michael S. German is at the University of California, San Francisco Diabetes Center, 513 Parnassus Avenue, HSW 1090, Box 0534, San Francisco, California 94143, USA.
   e-mail: mgerman@diabetes.ucsf.edu

Abstract

Pancreatic acinar cells have been reprogrammed in vivo into insulin-expressing cells by adenoviral delivery of three transcription factors.

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